1999 Grant PRIN –
2004 Grant MIPAF
2010 Grant PRIN
2017 Grant U Wageningen
1989-present Italian Society of Plant Biology (SIBV)
2007-present Italian Proteomics Association (itPA)
In the last years my interest has been focused on the study of the response of plants to environmental and biotic stress, mainly by means of a proteomic approach, which involved also the study of post-translational modifications of proteins. like phosphorylation. Arabidopsis thaliana plants have been subjected to temperature stress or challenged by plant pathogen elicitors and the response analyzed by 2D-electrophoresis and mass-spectrometry. A second issue concerns the characterization of the effects of plant secondary metabolites or fungal phytotoxins like fusicoccin and ophiobolin in plant and in human cells. At present a project concerning the involvement of the Unfolded Protein response (UPR) in the defense response of Arabidopsis plants to elicitor challenge or to the fungus Drechslera gigantea is under progress.
Rodolfo, C., Rocco, M., Cattaneo, L., Tartaglia, M., Sassi, M., Aducci, P.,Scaloni, A., Camoni, L., Marra, M. (2016). Ophiobolin a induces autophagy and activates the mitochondria pathway of apoptosis in human melanoma cells. PLoS ONE, 11(12) :
Cattaneo L, Cicconi R, Mignogna G, Giorgi A, Mattei M, Graziani G, Ferracane R, Grosso A, Aducci P, Schininà ME, Marra M (2015). Anti-proliferative effect of Rosmarinus officinalis L. extract on human melanoma A375 cells. PLOS ONE, 10:
Lomaglio T, Rocco M, Trupiano D, De Zio E, Grosso A, Marra M, Delfine S, Chiatante D, Morabito D, Scippa GS. (2015) Effect of short-term Cadmium stress on Populus nigraL. Detached leaves . J Plant Physiol. ;182: 40-8.
Rocco M., Arena S., Renzone G., Scippa GS., Lomaglio T., Verrillo F., Scaloni A. and Marra M. (2013) “Proteomic analysis of temperature stress-responsive proteins in arabidopsis thaliana rosette leaves”. Molecular Biosystems. 9: 1257-1267.
D’Ambrosio C., Arena S., Rocco M., Verrillo F., Novi G., Viscosi V., Marra M. and Scaloni A. (2012) “Proteomic analysis of apricot fruit during ripening”. J. Proteomics. 78: 39-57.
Huang C., Verrillo F., Renzone G., Rocco M., Scaloni A. and Marra M. (2011) “Response to biotic and oxidative stress in arabidospis thaliana: analysis of variably phosphorylated proteins”. J. Proteomics. 74: 1934-1949.
CorradoG, Agrelli D, Rocco M, Marra M, Rao R (2011) Systemin-inducible dense against pests are costly in tomato. Biologia Plantarum. 55: 305-311
M Rocco, G Corrado, S Arena , C D’Ambrosio, C Tortiglione, S Sellaroli, M. Marra , R Rao, A Scaloni. (2008). “The expression of tomato prosystemin gene in tobacco plants affects host proteomic repertoire”. Journal of Proteomics 71: 176-185.
C Guarino, S Arena, L De Simone, C D’ambrosio, S Santoro, M Rocco, A Scaloni, M Marra (2007) “ Proteomic analysis of the major soluble components in annurca apple flesh” Mol. Nutr. Food Res. 51: 255-262.
M Rocco, C D’Ambrosio, S Arena M Faurobert, A Scaloni and M Marra (2006) Proteomic analysis of tomato fruits from two ecotypes during ripening” Proteomics, 6: 3781-3791.
Visconti, S., Camoni, L., Marra, M.,and Aducci P. (2008) Role of the 14-3-3 C-terminal region in the interaction with the plasma membrane H+-ATPase. Plant Cell Physiology 49: 1887-1897.
Sottocornola, B., Visconti, S., Orsi, S., Gazzarrini, S., Giacometti, S., Olivari, C., Camoni, L., Aducci, P., Marra, M., Abenavoli, A., Thiel, G., and Moroni, A. (2006) The potassium channel KAT1 is activated by plant and animal 14-3-3 proteins. The Journal of Biological Chemistry 281: 35735-35741.
Camoni, L., Marra, M., Garufi, A., Visconti, S., and Aducci, P. (2006) The Maize Root Plasma Membrane H+-ATPase is Regulated by a Sugar-induced Transduction Pathway. Plant Cell Physiology 47: 743-747.