Research field
Biochemical characterization of plant extracts and evaluation of their potential biological effects (i.e. antineoplastic property, antioxidant power) on animal systems, both in vitro and in vivo. Biotechnological application of nanomaterials conjugated with plant secondary metabolites in cancer therapy. Cellular and molecular biology of plant systems subjected to environmental biotic and abiotic stresses. Plant microRNA bioactivity on animal and plant cells.
Publications
-Gismondi A., Reina G., Orlanducci S., Mizzoni F., Gay S., Terranova M.L. and Canini A. (2015). Nanodiamonds coupled with plant bioactive metabolites: a nanotech approach for cancer therapy. Biomaterials 38: 22-35.
-Gismondi A., Di Marco G. and Canini A. (2017). Detection of plant microRNAs in honey. PLoS ONE 12(2): e0172981.
-Gismondi A., Canuti L., Impei S., Di Marco G., Kenzo M., Colizzi V. and Canini A. (2013). Antioxidant extracts of African medicinal plants induce cell cycle arrest and differentiation in B16F10 melanoma cells. International Journal of Oncology 43 (4): 956-964.
-Gismondi A., Canuti L., Grispo M. and Canini A. (2014). Biochemical composition and antioxidant properties of Lavandula angustifolia Miller essential oil are shielded by propolis against UV radiations. Photochemistry and Photobiology 90 (3): 702-708 – [Erratum, Photochemistry and Photobiology 90 (5): 1214].
-Forni C., Braglia R., Mulinacci N., Urbani A., Ronci M., Gismondi A., Tabolacci C., Provenzano B., Lentini A. and Beninati S. (2014). Antineoplastic activity of strawberry (Fragaria × ananassa Duch.) crude extracts on B16-F10 melanoma cells. Molecular BioSystems 10: 1255-1263.
-Di Marco G., Gismondi A., Canuti L., Scimeca M., Volpe A. and Canini A. (2014). Tetracycline accumulates in Iberis sempervirens L. plants through apoplastic transport inducing oxidative stress and growth inhibition. Plant Biology 16 (4): 792-800.
-Impei S., Gismondi A., Canuti L. and Canini A. (2015). Metabolic and biological profile of autochthonous Vitis vinifera L. ecotypes. Food & Function 6: 1526-1538.
-Giovannini D., Gismondi A., Basso A., Canuti L., Braglia R., Canini A., Mariani F. and Cappelli G. (2016). Lavandula angustifolia Mill. essential oil exerts antibacterial and anti-inflammatory effect in macrophage mediated immune response to Staphylococcus aureus. Immunological Investigations 45 (1): 11-28.
-Gismondi A., Nanni V., Reina G., Orlanducci S., Terranova M.L. and Canini A. (2016). Nanodiamonds coupled with 5,7-dimethoxycoumarin, a plant bioactive metabolite, interfere with the mitotic process in B16F10 cells altering the actin organization. International Journal of Nanomedicine 11: 557-574.
-D’Angeli S., Matteucci M., Fattorini L., Gismondi A., Ludovici M., Canini A. and Altamura MM. (2016) OeFAD8, OeLIP and OeOSM expression and activity in cold-acclimation of Olea europaea, a perennial dicot without winter-dormancy. Planta 243(5): 1279-1296.
-Gismondi A., Di Marco G., Canuti L. and Canini A. (2017) Antiradical activity of phenolic metabolites extracted from grapes of white and red Vitis vinifera L. cultivars. Vitis 56, 19–26.
-Gismondi A., Trionfera E., Canuti L., Di Marco G. and Canini A. (2017). Royal jelly lipophilic fraction induces antiproliferative effects on SH-SY5Y human neuroblastoma cells. Oncology Reports 38(3): 1833-1844.
-Mastropasqua M.C., D’Orazio M., Cerasi M., Pacello F., Gismondi A., Canini A., Canuti L., Consalvo A., Ciavardelli D., Chirullo B., Pasquali P. and Battistoni A. (2017). Growth of Pseudomonas aeruginosa in zinc poor environments is promoted by a nicotianamine-related metallophore. Molecular Microbiology 106(4): 543–561.